Playing Doctor: Meet the Real-Life Loves of More Than 25 Grey’s Anatomy Stars [PHOTOS]

Ellen Pompeo (Meredith Grey)

Grey’s Anatomy star Ellen Pompeo has been married to music producer Chris Ivery since 2007. The twosome has three kids: Sienna, Stella, and Eli.

Chandra Wilson (Miranda Bailey)

Wilson has been in a relationship with her significant other for over 30 years and they share three children: Sarina, Joylin, and Michael. The star has kept her beau’s name out of the media to protect their privacy.

Patrick Dempsey (Derek Shepherd)

Grey’s Anatomy’s former “McDreamy” Patrick Dempsey married Jillian Fink in 1999. They have three children: a daughter, Tallula and twin boys, Sullivan and Darby. The pair nearly called it off in 2015 but later reconciled.

Justin Chambers (Alex Karev)

Chambers, whose character Karev left Seattle to reunite with his former partner Izzy, married his wife Keisha in 1993. He and the former model have five children together: Isabella, twins Maya and Kaila, Eva, and Jackson.

Sandra Oh (Cristina Yang)

Yang was Meredith Grey’s “person” and was played by Sandra Oh. Oh’s person is Russian artist Lev Rukhin, the man she’s been dating for several years. She was previously married to director/screenwriter/producer Alexander Payne.

Katherine Heigl (Isobel “Izzy” Stevens)

One of Grey’s Anatomy original characters, Izzy Stevens exited the series when Heigl left in 2010. Three years prior to that, the actress married her husband, singer/songwriter Josh Kelley. They have three children: Nancy, Adalaide, and Joshua.

James Pickens Jr (Richard Webber)

James Pickens Jr, who plays Grey’s Anatomy’s esteemed Dr. Richard Webber, has been married to his wife Gina since 1984. They have two children together: Gavyn and Carl.

T.R. Knight (George O’Malley)

Grey’s Anatomy’s beloved OG character, George, may have died many seasons ago, but he keeps popping up, most recently in the beach scenes when Meredith was hospitalized with Covid. Knight, who remains a fan favorite, married his partner, ballet dancer/writer, Patrick Leahy, back in 2013.

Kelly McCreary (Maggie Pierce)

Maggie’s married to Winston on Grey’s Anatomy, and offscreen, McCreary married her husband Pete Chatmon, who she met on set, in 2019. They have one child together.

Jessica Capshaw (Arizona Robbins)

Capshaw married entrepreneur Christopher Gavigan back in 2004, well before joining Grey’s Anatomy in 2009, where she later became part of the iconic Arizona and Callie pairing. Capshaw and Gavigan have four children together: Eve, Luke, Poppy, and Josephine.

Eric Dane (Mark Sloan)

Grey’s Dr. McSteamy, Mark Sloan, was played by Eric Dane. Offscreen, the actor was married to soap alum Rebecca Gayheart, who played Hannah Mayberry on Loving. Though she filed for divorce in 2018, she hasn’t followed through with it, and the pair have been together in vacation photos with their kids, both this year and last. So it’s kind of an “are they or aren’t they?” situation.

Camilla Luddington (Jo Wilson)

Jo hasn’t been so lucky in love, but Luddington has been happily married to actor Matthew Alan since 2019. The pair has two children together: Hayden and Lucas.

Kim Raver (Teddy Altman)

Raver is married both on and off-screen. While Teddy’s with Owen (albeit in a sometimes contentious union), Kim wed director Manu Boyer in 2000. They have two sons, Luke and Leo.

Chyler Leigh (Lexie Grey)

Leigh, who left Grey’s Anatomy when her character Lexie tragically died following a plane crash, married actor Nathan West in 2002. The pair has three children: Noah, Taelyn, and Anniston.

Isaiah Washington (Preston Burke)

Washington, who played renowned surgeon Dr. Preston Burke from 2005 – 2007 and returned in a 2014 episode, has been married to Jenisa Garland since 1996. The couple share three children: Tyme, Iman, and Isaiah Jr.

Giancomo Gianniotti (Andrew Deluca)

Gianniotti tried his luck with none other than Meredith Grey as Grey’s Anatomy’s Deluca, and it didn’t pan out. In real life, the actor is married to hair and make-up artist Nichole Gustafson. The good-looking duo tied the knot in 2019.

Richard Flood (Cormac Hayes)

Flood’s time on Grey’s wasn’t as long as some fans would have liked, but Hayes was an interesting character during his run. Off-screen, he is married to American-Italian actress Gabriella Pession. The happy couple has one son, Giulio.

Chris Carmack (Atticus Lincoln)

Link didn’t fare so well in his relationship with Amelia, but there’s still hope for Link and Jo! In real-life, Carmack is married to Erin Slaver. The two wed in 2018 and have two daughters, Kai and Cielle.

Scott Speedman (Nick Marsh)

The transplant surgeon who seems destined to get back together with Meredith on Grey’s Anatomy is played by well-known actor Scott Speedman. He welcomed his first child, a daughter named Pfeiffer, with partner Lindsay Rae Hoffman in 2021. The pair began dating in 2017.

Greg Germann (Thomas Koracick)

Another character that was unlucky in love on Grey’s, Koracick ultimately lost Teddy to Owen. Happily, in real life, Germann has been married to his beautiful wife Martha Champlin since 2013.  He has a son, Asa, from his previous marriage to Christine Mourad.

Debbie Allen (Catherine Avery)

While Catherine has Richard Webber, Debbie Allen has Norm Nixon, the former pro basketball player she married in 1984. They have three children together: Norman Jr., DeVaughan, and Vivian.

Jeffery Dean Morgan (Denny Duquette)

Morgan portrayed the unforgettable Denny on Grey’s Anatomy from 2006 – 2009. Though he was divorced from his first wife Anya by then, in 2019 he remarried. Morgan and Hilarie Burton of One Tree Hill fame tied the knot after 5 years of dating.

Kate Burton (Ellis Grey)

Kate Burton played the inimitable Ellis, mother of Meredith Grey and ex-lover of Richard Webber on the ABC series. Off-screen, Burton has been married to director Michael Ritchie since 1985. They have two children: Morgan and Charlotte

Scott Foley (Henry Burton)

Though he was only on Grey’s from 2010 – 2012, Henry left an impression on fans. Foley, who was previously married to Jennifer Garner, is now wed to Marika Dominczyk, who played Dr. Eliza Minnick on the show from 2016 – 2017. They have three children: Malina, Keller, and Konrad.

Loretta Devine (Adele Webber)

Grey’s Anatomy’s Adele Webber, Devine left the series back in 2013 when her character died following a battle with Alzheimer’s. Off-screen, the actress has been married to Glenn Marshall since 2001. She was previously wed to Lamar Tyler.

Harry Shum Jr. (Daniel Kwan)

Newcomer to Grey’s, Harry Shum Jr, is married to actress Shelby Rabara. They tied the knot in 2015 and have one child, Xia.